Manuela Stoicescu
Oradea University
Romania
Title: Beta-Human Chorionic Gonadotrophin (β-HCG total) as a tumor marker in pregnancy
Biography
Biography: Manuela Stoicescu
Abstract
Beta-Human Chorionic Gonadotrophin (β HCG total) represents a substance that is usually secreted by the placenta in the course of pregnancy. This is why it is used as a pregnancy test, because the values are high in the first trimester of the pregnancy. But the determination of the β HCG total is also can used as a tumor marker in order to detect gestational trophoblast diseases such as the hydatidiform mole and choriocarcinoma and germ cell tumors of the ovaries and testicle. Nevertheless the young pregnant hypertensive patient, with increased values of total β HCG after the first trimester of pregnancy, cannot be left to be interpreted only within the pregnancy context, but these must be taken into account as a possible choriocarcinoma diagnosis. This tumoral marker should be performed as a screening test in young pregnant women with severe values of blood pressure, after the first month of pregnancy, in order to detect an unknown choriocarcinoma, thus the blood pressure values should not be interpreted only within the pregnancy context, of course if other causes of secondary hypertension in pregnant woman were excluded. In the future the stem cell therapy it is posible to be a solution for this patients with choriocarcinoma unsolved yet.