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Paul J. Davis

Paul J. Davis

Chair, Department of Medicine
Albany College of Pharmacy and Health Sciences
USA

Biography

Dr. Davis is a graduate of Harvard Medical School and had his postgraduate medical training at Albert Einstein College of Medicine and the NIH. His academic positions have included Chair, Department of Medicine, Albany Medical College. He has served as President, American Thyroid Association and as a member of the Board of Directors of the American Board of Internal Medicine. His scientific interests include molecular mechanisms of actions of nonpeptide hormones, particularly, thyroid hormone. He has co-authored more than 200 original research articles and 30 textbook chapters and he has edited three medical textbooks.

Research Interest

Dr. Davis directs a group of scientists who have defined molecular mechanisms for many nongenomic, plasma membrane-initiated actions of thyroid hormone, including actions on plasma membrane ion transporters, intracellular protein trafficking, phosphorylation of nuclear hormone receptors and of p53 and on transcription of specific genes. They have described the cell surface receptor for thyroid hormone on integrin avb3 and the actions of tetraiodothyroacetic acid (tetrac) and reformulated (nanoparticulate) tetrac initiated at this plasma membrane receptor that are anti-angiogenic and anti-cancer by multiple cell surface and intracellular pathways.